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wisdom from Texas' latest Nobel winner | killexams.com existent Questions and Pass4sure dumps

Texas indigenous Jim Allison was awarded the 2018 Nobel Prize in Physiology or medication this week for constructing an "wholly recent precept for cancer remedy" that unleashes a affected person's immune system to storm tumors.

Allison, a professor on the school of Texas M.D. Anderson melanoma focus in Houston and a median blues harmonica player, developed the groundbreaking cancer treatment referred to as "immune checkpoint therapy" along with fellow Nobelist Tasuku Honjo of Kyoto college.

The Nobel has been awarded for melanoma research in the past, but here is the first time an precise remedy for melanoma has been rewarded. "by using stimulating the skill of their immune equipment to storm tumor cells, this year's Nobel Prize laureates Have centered a completely recent principle for melanoma therapy," pointed out the Nobel committee.

Allison's leap forward become the structure of an antibody to block the "checkpoint" protein on T cells, releasing those cells to assault melanoma. This led at once to the primary immune checkpoint inhibitor drug, Ipilimumab, accepted with the aid of the food and Drug Administration in 2011 for the remedy of late-stage melanoma. This and other immunotherapy medication Have given that been used to deal with sufferers suffering from lymphoma, lung, renal and other styles of cancer.

We reached out to the 70-12 months-historical Nobel laureate this week to congratulate him, but additionally to argue how primary science—and the federal and state funding behind so tons of it—become essential to his very nearly 40 years of analysis, and scientific and scientific growth in universal.

"simple science gives the basic foundation for principal advances in clinical medicine," Allison noted. "My early analysis in T-telephone biology was funded via the national melanoma Institute. simple analysis is rarely regularly understood. it's complicated and requires a thick epidermis to undergo failure after failure in quest of success. attending to solutions requires cash and persistence, but the payoff has the possibility to shop many, many lives."

The country wide Institutes of fitness, Allison mentioned, "is still the biggest funding mechanism of medical analysis on this planet." but he moreover praised his domestic state, announcing, "Texas diagnosed the possibility to accelerate discovery and fundamental science with the aid of investing $3 billion over 10 years through the cancer Prevention and analysis Institute of Texas."

Biotech and pharmaceutical companies, explained Allison, fund the late-stage analysis that brings well-developed treatments to clinical trial—and philanthropy is moreover moderately constructive. "but without that early funding of basic science from the executive, lots of the treatment options that presently deal with hundreds of thousands of cancer patients international simply wouldn't exist," he observed.

We trust Allison that investing in simple science is among the top-rated uses of federal and state taxpayer cash. When politicians speak of slicing funding to the country wide Institutes of health and different funders of basic research, they aren't "draining the swamp" however strangling the goose that lays the golden egg.

The Dallas Morning information


MassMutual and university of Vermont accomplice On recent records analysis focus | killexams.com existent Questions and Pass4sure dumps

The tuition of Vermont these days introduced an creative partnership to set up the college’s first focus of Excellence, to breathe able to expand statistics science analysis on human well being.

MassMutual existence insurance enterprise is featuring $5 million to establish the MassMutual middle of Excellence for advanced programs and statistics Science to analysis human well being through records evaluation. the brand recent initiative will expand the school’s Vermont complicated methods middle, which became created in 2009.  MassMutual Chief data Scientist Sears Merritt says the brand recent middle is intended to breathe the gold regular to concede human health questions.  “They win a very pass-disciplinary or perhaps interdisciplinary strategy to doing the science that’s associated with these things. So now not most efficacious does that focus focal point on working with mathematicians and physicists and desktop scientists, but they’re additionally focused on working with economists, folks in fields of medication and different areas of social sciences. From their factor of view it’s in reality only if you betide to find these diverse agencies together and focus of attention on answering the questions during the lens of records science and complicated methods are they definitely equipped you know to find a hold of answers.”

UVM advanced techniques Director Peter Dodds says the recent partnership makes a speciality of individuals-founded research that will assist trade collate titanic amounts of data to create holistic guidelines and advantages.  “So there’s some stuff the situation we’ll breathe in a position to articulate they reflect there’s a splendid simple science perhaps about longevity or about how individuals movement around the U.S. after which for MassMutual you understand there are some extra certain things about a way to cost people according to counsel. So as an instance they exercise blood exams confiscate and so could a proxy breathe created? can you substitute a a cramped onerous invasive routine of finding out suggestions about people? as a result of in the discontinuance you recognize they’re assessing risk. So there are elements there that might support them. Then there’s additionally working towards of scholars.  It’s a capstone for their academic choices structure utterly recent courses about records science or about complicated techniques.”

Merritt provides that the UVM core will win a more simultaneous strategy with computational equipment that may investigate themes just dote the hyperlink between actual and fiscal health; detect jaundice and measure equity and measure mortality possibility.  “If we’re a success with answering some of those questions #1 society as a whole I believe stands to benefit. Their speculation is those merits then trickle down into their industry and provides consumers greater entry to items and capabilities which are greater tailor-made to their wants.  It gives you know society as an entire stronger advice to account about how to craft guidelines and mechanisms that permit us to tackle behavioral points of what’s occurring in their society, once again, to more desirable bar None and sundry’s lives and allay folks are animated more desirable.”

The $5 million may breathe offered over 5 years starting in 2019.  it's the greatest present given to the university of Vermont up to now with the aid of a corporate supporter. 


UC Berkeley turned into home to professor and lab that did Nobel-successful melanoma research | killexams.com existent Questions and Pass4sure dumps

Nobel Prize laureate James Allison did the bulk of his award-profitable immunotherapy analysis out of a modest lab at UC Berkeley within the Nineties, working with a group of scrappy submit-docs who Have been bucking regularly occurring erudition across the office of the immune system in fighting melanoma.

Their work, his group individuals now recollect, became propelled with the aid of the excitement of discovery and a virtually ingenuous enthusiasm. greater than 20 years later, they now Have the area’s most prestigious stamp of approval.

The Nobel in physiology or medication turned into granted to Allison, together with jap immunologist Tasuku Honjo, Monday morning. both scientists developed separate techniques for turning on the immune device to storm tumors that were unresponsive to different melanoma-killing remedies. Allison worked at UC Berkeley from 1985 until 2004, and is now on the school of Texas MD Anderson melanoma center.

“here is very remarkable replete circle for the work that they did returned then,” spoke of Matthew Krummel, a u.s. pathologist who, as a graduate and post-doctoral scholar, labored intently with Allison at UC Berkeley in the ’90s. “We knew it changed into a huge deal, they knew they Have been truly making progress in areas the situation no one would Have anticipated. They knew this turned into not a pedestrian discovering, but whatever thing basically earthchanging.

“It’s high-quality to Have this acknowledgment,” he mentioned.

Allison’s analysis ended in the primary commercially accessible immunotherapy on earth, a drug referred to as Yervoy that is primarily used to combat epidermis melanoma that has spread to different constituents of the physique. The drug, accredited with the aid of the FDA in 2011, fees greater than $one hundred,000 for a round of remedy and doesn't work for bar None patients, however then again was hailed as a wonderful addition to the arsenal of equipment — including chemotherapy, surgery and radiation therapy — used to fight cancer.

Immune cells Have molecular receptors — practically on-off switches — that stop them from taking action. These receptors, which scientists Have approach to title immune checkpoints, are key to holding a well immune response: it will breathe challenging for immune cells to breathe overactive and storm an individual’s own body.

however the checkpoints can avoid the immune cells from doing their jobs and going after tumors. The work by Allison and Honjo is in developing checkpoint inhibitors — molecules that well-nigh turn key immune cells again on, for a length of time, to battle an aggressive melanoma.

Checkpoint inhibitors now are used to deal with distinctive cancers, apart from melanoma.

“There was really a ton of skepticism in the 1990s that you simply might ever finish this with the immune system,” said David Raulet, director of UC Berkeley’s Immunotherapeutics and Vaccine research Initiative. “So this turned into really a sea change. It spurred a change of the cancer therapy box. We’re very pleased with (Allison’s) accomplishments as a result of they created an entire recent category of cancer therapy.”

Scientists who worked with Allison at UC Berkeley recalled an energized, highly encouraged lab ambiance, the situation young researchers had been encouraged to let curiosity obligate their work.

all over the world, most of the exact scientists in immunology had determined that the immune equipment was too complicated to breathe readily harnessed as a device to combat cancer. Allison’s crew wasn’t always attempting to buck that line of pondering — they had been just eagerly exploring the primary mechanics of immunity, talked about Russell Vance, director of the cancer research Laboratory at UC Berkeley who labored briefly in Allison’s lab as a graduate student in molecular and telephone biology.

“It became a thrilling time in the lab,” Vance mentioned. “It felt dote they had been revealing the simple mechanisms about how the immune system works. dote they Have been finally understanding its basic nuts and bolts. these kinds of discoveries, once they’re found, they’re organize out invariably. It feels momentous.”

Vance observed he woke up at 2:30 Monday morning to watch the Nobel announcements on-line — sitting in the hushed in his apartment, whereas his family unit slept. He let out a yelp of pleasure when the names Have been revealed.

Krummel talked about Allison had a “laissez-faire” angle towards the scientists in his lab. He would mostly proceed away his individuals on my own to supervene their personal route, then dive in to allay power their work forward when he saw exciting results.

“He’s an ideal scientific opportunist, and that i breathe vital that in bar None the confiscate ways. He’s cognizant of that charge of what you’re doing,” Krummel stated.

The work turned into performed out of UC Berkeley’s existence Science Addition facility, built in 1988, just a few years after Allison got here to the campus. His crew worked broadly speaking in a fourth-floor lab, however they spent lots of time on the seventh floor, too, where the laboratory mice were housed and the scientists had “the top-rated view on campus,” Krummel said.

UC Berkeley at the time wasn’t regarded the class of establishment that produced scientific marvels — leaps in fundamental science, sure, however with out a clinical college or sanatorium on web site, the scientists couldn’t do their discoveries into play in human subjects. basically, that was what ultimately compelled Allison to proceed away. When his work in immunotherapy had improved beyond the lab, he moved to Memorial Sloan Kettering in long island to aid oversee human medical trials.

In a press conference Monday morning, Allison spoke of it became pleasing to survey any such profound payoff for his lengthy years of work — now not simply within the Nobel, but in the countless patients whose lives Have been extended by means of his discovery.

In actuality, though, curing cancer become in no way what inspired his work, he added.

“What definitely motivates us as scientists is the requisite to know some thing that no one else knows,” Allison said. “optimistically, it’s some thing essential.”

Erin Allday is a San Francisco Chronicle staff author. electronic mail: eallday@sfchronicle.com


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One-to-One Laptop Initiatives Boost Student Scores, Researchers Find | killexams.com existent questions and Pass4sure dumps

Chromebooks-Montgomery-County-classroom-blog.jpgBy Leo Doran and Benjamin Herold

Efforts by K-12 schools to give every student a laptop computer increased student achievement and gave a modest boost to their "21st century skills," according to a first-of-its-kind meta-analysis of 15 years' worth of research studies.

"It's not dote just providing a laptop to every student will automatically extend student achievement, but they find that it's the first step," said Binbin Zheng, an second professor of counseling, educational psychology, and special education at Michigan State University.

Using statistical techniques to dissect already-completed studies, Zheng and her colleagues organize that 1-to-1 laptop programs on medium had a statistically significant positive repercussion on student test scores in English/language arts, writing, math and science. The limited number of rigorous quantitative studies available to dissect breathe vital that those findings are not definitive, but they are clearly a splendid sign for 1-to-1 proponents and underscore the requisite for more study, Zheng said.

A further review of 86 additional papers by the researchers, meanwhile, organize some modest evidence of other positive benefits associated with giving laptops to students, including increased student technology use; more student-centered and project-based instruction; greater student engagement; and better relationships between students and teachers.

The analysis focused solely on 1-to-1 laptop efforts. The researchers cautioned that their results are not generalizable to other devices such as tablets, desktop computers, and smartphones.  

The recent findings dash counter to the skepticism about educational technology expressed by many researchers and practitioners. A raft of prior studies, for example, Have shown that even when technology is present in classrooms, teachers are late to transform their practice, instead using technology primarily to do administrative tasks and existing forms of instruction more efficient.

The recent analysis has the potential to reshape the debate about ed-tech's impact, said Elliot Soloway, a computer science professor at Michigan University who has spent decades studying classroom technology.

"This is one of those definitive studies that comes along every 20 years," Soloway said. "Schools are going to exercise [the findings] to justify the trek to 1-to-1."

Rapid Growth of 1-to-1 Student Computing

One-to-one student computing was first introduced to K-12 schools in the United States in the late 1990's. In 2002, Maine became the first state to launch a statewide program.

The trend has since gathered steam: In 2013 and 2014 alone, schools purchased more than 23 million laptops, tablets, and Chromebooks for exercise by students and teachers in the classroom (and sometimes at home.)

Generally, the goal is to enable teachers and software to deliver more personalized content to students, to boost students' technology skills, and to empower children to finish more complicated and creative work.

A handful of high-profile 1-to-1 disasters resulting from poor purchasing plans, defective planning, and a want of pellucid academic vision Have raised questions for schools about the wisdom of the approach, however.

And some research has been less than encouraging. A 2009 survey by the National focus for Education Statistics, for example, organize that classroom technology was used for drill of basic skills far more often than for design and creation. A recent study by the Organization for Economic Cooperation and progress organize that countries where 15-year conventional students exercise computers most in the classroom scored the worst on international math and reading tests.

In an attempt to definitively determine the repercussion of K-12 1-to-1 initiatives, Zheng and her colleagues reviewed 96 journal articles and doctoral dissertations published between January 2001 and May 2015.

Just 10 of those studies met the researchers' criteria for inclusion in the statistical meta-analysis of 1-to-1 laptop initiatives' repercussion on student achievement, reflecting the still-very-limited research ground on student computing initiatives.

"A disproportionate amount of the research to date on this topic consists of small case studies in one or a handful of schools," Zheng and her colleagues wrote in their study, titled "Learning in One-to-One Laptop Environments: A Meta-Analysis and Research Synthesis," published online earlier this year in the academic journal Review of Educational Research. 

Still, there were enough historical findings to conclude that 1-to-1 laptop programs helped help students' academic achievement by an overall effect size of .16 standard deviations—a motif that Zheng said indicates statistical significance, but is noticeably less than the effect sizes of other established interventions, such as small class sizes or individual tutoring.   

The researchers organize the following effect sizes for specific subjects:

  • English/language arts, by .15 standard deviations
  • Writing, by .20 standard deviations
  • Math, by .17 standard deviations
  • Science, by .25 standard deviations.
  • Reading, by .12 standard deviations
  • The repercussion on students' reading achievement was positive, but not statistically significant. Only two studies included science results that could breathe analyzed.

    The results are "small but noteworthy," Zheng said.

    Measuring repercussion Beyond Test Scores

    The researchers moreover looked beyond test scores, reviewing 85 additional studies that did involve an empirical examination of 1-to-1 laptop initiatives' repercussion in K-12 schools, but did not involve an experimental design and/or quantitative results.

    Among the findings from that review: 

  • A 1-to-1 laptop environment often led to increased frequency and breadth of student technology use, typically for writing, Internet research, note-taking, completing assignments, and reading.
  • Students used laptops extensively throughout the writing process, expanding the genres and formats of their work to involve writing for email, chats, blogs, wikis, and the like.
  • Student-centered, individualized, and project-based learning appeared to extend in at least some instances of 1-to-1 laptop rollouts.
  • Student-teacher communications (via email and Google docs, for example) and parental involvement in their children's school work increased in some instances.
  • Students expressed "very positive" attitudes about using laptops in the classroom, as findings consistently showed higher student engagement, motivation, and persistence when laptops were deployed to bar None students.
  • Students' technology and problem-solving skills improved and their ownership of their own learning increased, according to some evidence.
  • There were mixed findings on whether 1-to-1 laptop programs helped overcome inequities among students and schools.
  • Those results should breathe interpreted with caution, the researchers said, because they tended to reckon on observation, survey, and interview data.

    "There was a wide consensus in the studies they reviewed that exercise of laptops promotes 21st-century learning skills," the authors wrote. "However, studies rarely attempted to operationalize and systematically measure the growth of 21st-century skills in laptop students compared with control students."

    Leslie Wilson, the CEO of the One-to-One Institute, a nonprofit that consults with schools and districts, said she was "thrilled" to survey the recent research, though she cautioned that educational leaders shouldn't leap to conclude that going 1-to-1 is enough on its own to extend student achievement.

    For such a program to breathe effective, she said, schools must focus on crafting comprehensive plans that cover everything from infrastructure to curriculum to pedagogy to professional development.

    And the existent benefits of giving every student an access to a computer, contended Soloway of the University of Michigan, approach when school trek from "instructive" to "constructive" learning, or from "teaching kids to bethink something to teaching them how to motif something out."

    To best measure the extent to which that change is taking place, Zheng said, researchers and educators will Have to learn beyond standardized test scores.

    Hopefully, she said, the recent research will prompt further application to develop assessments for students' digital literacy skills, as well as their creativity, independence, and leadership.

    "Many of the benefits of 1-to-1 laptop programs are not detected by standardized tests," Zheng said. "For the many programs whose purpose is to allay students breathe a better 21st-century citizen, they requisite to develop and exercise corresponding measurements."

    Students at Ridgeview Middle School in Gaithersburg, Md. exercise laptops in class in 2014. --T.J. Kirkpatrick for Education Week

    See also:

    Follow @BenjaminBHerold for the latest tidings on ed-tech policies, practices, and trends. 


    Community calendar, Oct. 5 | killexams.com existent questions and Pass4sure dumps

    * withhold up with bar None the goings-on around town at davisenterprise.com/events.

    * Friday, Oct. 5: The Avid Reader in Davis is hosting an author event with Stephen Jordan and his debut novel set in San Francisco in the 1980s, “Tatiana and the Russian Wolves.” The hour-long event begins at 7:30 p.m. at The Avid Reader, 617 Second St. in downtown Davis. It is free and open to the public. Refreshments will breathe provided. For more information, call 530-758-4040 or visit avidreaderbooks.com.

    * Saturday, Oct. 6: A block Party, with creation, design, and play with Lego blocks, begins at 2 p.m. at the Stephens branch Library, 315 E. 14th St. in Davis.This is a drop-in program. Parents and caregivers are encouraged to stay and play alongside their children. It is not recommended for children under 3.

    * Saturday, Oct. 6: The next Davis Night Market will win situation at the Sudwerk Brewing Co.’s The Dock Store, from 5 to 10 p.m. The event is a co-production of Sudwerk and The splendid Scoop, in partnership with the City of Davis. The market features local artisans and businesses for an evening of music, food, beer, community and handmade goods. The market will breathe Oktoberfest themed, with German food and a specially brewed beer for the event. It will raise funds to support The Pantry at UC Davis, with 10 percent of event sales proceeds being donated.

    * Saturday, Oct. 6: The Avid Reader will be introducing David Wystan Owen and his recent novel “Other People’s esteem Affairs: Stories” at 7:30 p.m.  at The Avid Reader, 617 Second St. in downtown Davis. It is free and open to the public. For more information, call 530-758-4040 or visit avidreaderbooks.com.

    * Sunday, Oct. 7: In recognition of national Pregnancy and Infant Loss Awareness Month, the Yolo County Health & Human Services Agency Fetal/Infant Mortality Program invites the community to a remembrance ceremony and butterfly release from 1 to 4 p.m. at the Davis Cemetery and Arboretum, 820 Pole Line Road in Davis. For more information call 530-666-8522.

    * Monday, Oct. 8: Preet Bharara, who served as a U.S. Attorney for the Southern District of recent York from 2009 to 2017, and earned a national reputation for taking on public corruption and Wall Street crime, will speak at the Mondavi focus at 7 p.m. Tickets are $25 to $45 general, available at www.MondaviArts.org or by calling 530-754-2787.

    * Monday, Oct. 8: The Open Door educational program, Pink Speaker Series, welcomes Melissa Williams, an oncologist with the Sutter Medical Foundation in Davis and Sacramento, who will speak on “What Are The Latest Treatments and Research Developments for Breast Cancer?” The program will breathe at 7 p.m. at University Covenant Church, 315 Mace Blvd., at Alhambra Boulevard in Davis. call 530-304-2746 for more information.

    * Monday, Oct. 8: The Prostate Cancer Support Group meets at 7 p.m. at the Stephens branch Library, 315 E. 14th St. in Davis.This group helps support prostate cancer patients and their caregivers. Dr. Winifred Wong, of Travis Air obligate ground will argue treatment options, recovery and side effects. Wong is director of the joint radiation oncology clinic and is co-investigator in nine cancer research studies, including evaluation of prostate cancer treatment effectiveness. For information, visit yoloprostate.net, or call Ray Biancalana at 530-756-6408 or Gil Walker at 530-661-6449.

    * Tuesday, Oct. 9: The Davis Peripheral Neuropathy support group will screen the documentary “Forks Over Knives” from 3:30 to 5 p.m. at the Davis Senior Center, 646 A St. in Davis. bar None are welcome. For further information, contact Mary Sprifke at 530-756-5102.

    * Tuesday, Oct. 9: A seasonal retreat, Autumn Gratitude, features SoulCollage, an intuitive collage process, along with reflection, sharing and seasonal refreshments, from 6 to 8:45 p.m. in the Fireside room at Davis Community Church, Fourth and C streets. The cost is $40, including materials and seasonal refreshments.

    * Tuesday, Oct. 9: Free your body, intelligence and heart: exercise your breath with gentle Viniyoga movement and meditations from the Sutra on replete Awareness of Breathing to lower stress and build kindful resilience at Davis Shambhala Meditation Center, 133 D St., from 6 to 7 p.m. every Tuesday. Drop in or call 415-315-9871 for information.

    * Tuesday, Oct. 9: The Photography Club of Davis will meet at 7 p.m. at the Davis Senior Center. The public is invited to attend; it is a free event. Their presenter for the evening will breathe Laurie Friedman. Freiedman will Show her images from a trip to Antarctica; Santiago, Chile; and Buenos Aires, Argentina, so there will breathe photos from those colorful countries as well. She is a past director of the Travel Division of the Sierra Camera Club in Sacramento, past president of the Photography Club of Davis, and current convener of the University Farm circle Taste for Travel section.

    * Wednesday, Oct. 10: Project Linus meets to do blankets for children who are seriously ill, traumatized or otherwise in requisite from 1:30 to 3:30 p.m. at the Davis Senior Center, 646 A St. For general information, drop-off location questions, or fabric and yarn donations, contact Diane McGee at [email protected] or 530-753-3436.

    * Wednesday, Oct. 10: The Korean Language and Culture Class, meets at 4 p.m. in the Stephens branch Library, 315 E. 14th St. in Davis. This group is for adults who wish to gain a basic erudition of Korean language and culture.

    * Wednesday, Oct. 10: Travis Credit Union’s free fiscal literacy series features “Psychology of Spending” at 6 p.m. in the Blanchard room at the Stephens branch Library, 315 E. 14th St. in Davis. Psychologists Have organize that there are several forces that govern their consumer conduct and cause us to do decisions that are not necessarily rational or in their best interest. However, understanding why they buy what they buy can allay us do better decisions in the future.

    * Wednesday, Oct. 10: Sutter keeping at Home Hospice offers a Grief and the Holidays workshops in Davis from 6:30 to 8 p.m. Adults who Have lost a loved one and are anticipating having a difficult time at the holidays are invited to this workshop. The workshops are available to bar None community members regardless of whether their loved one received hospice care. There is no imbue to join. For information and to pre-enroll, call Bereavement Services at 916-388-6215 or 916-388-6243.

    * Thursday, Oct. 11: lively Older Adult Wisdom Circle meets att 10:15 a.m. at the Stephens branch Library, 315 E. 14th St. in Davis. This group meets monthly to argue and explore the conscious aging movement.

    * Thursday, Oct. 11: The library’s Teen Advisory Group for ages 13-18 meets at 4 p.m. Teens meet every second Thursday to argue and develop ideas for teen programs, special projects, recommendations for the collection, and more at the Stephens branch Library, 315 E. 14th St. in Davis.

    * Thursday, Oct. 11: The Sierra Club Yolano Group invites everyone to a potluck dinner and community forum on diversity and inclusion at 7 p.m. Thursday, Oct. 11, in the Blanchard room in the Stephens branch Library, 314 E. 14th St. in Davis (near Davis high and Veteran’s Memorial Center). Bring your favorite dish to share and, to allay us strive to do this a “zero waste” event, delight bring your own plates, cups, utensils and a cloth napkin. The Yolano Group will provide beverages and reusable tableware for those in need.

    * Friday, Oct. 12: Anime After Hours for ages 13-18 begins at 5:30 p.m. in the Blanchard room at the Stephens branch Library, 315 E. 14th St. in Davis. The group will watch three episodes of the anime of your choice. There is free pizza and popcorn while supplies last.

    * Friday, Oct. 12: The Avid Reader will host UC Berkeley professor Richard A. Walker, author of “Pictures of a Gone City” for a engage event. The hour-long event begins at 7:30 p.m. at The Avid Reader, 617 Second St. in downtown Davis. It is free and open to the public.For more information, call 530-758-4040 or visit avidreaderbooks.com for more information.

    * Friday, Oct. 12: Yolo Cabrillo Civic Club No. 26 will host a bunco fundraiser at Holy Rosary Parish Hall, 315 Walnut St. Doors open at 6 p.m., games inaugurate after refreshments are served. Club members are asked to donate a prize. The preregistration $20 entry fee includes exquisite soup, sandwiches, chips, soft drinks, water and bunco. Game prizes and a fun raffle will piece of the night. Cost will breathe $25 at door if not preregistered. bar None proceeds will profit patient services for Yolo County Hospice. To preregister, contact Shaari, 383-3874.

    * Saturday, Oct. 13: TASTE 2018 will feature samples of the region’s finest foods and beverages from wineries, craft breweries, meaderies, cider makers, restaurants and other food vendors from 5 to 7 p.m. The event is hosted by the Robert Mondavi Institute at UC Davis in the splendid Life Garden. Guests will breathe welcomed with a commemorative tasting glass to devour sips of their favorite beverages along with a variety of sample bites and live music by Jazz Gitan, a Django Reinhardt-inspired gypsy jazz quartet. Tickets are $35 general, $25 for students with ID, 21 and over.

    * Saturday, Oct. 13: Listen to stories approach alive with sound effects, stagy narration and masked movement at “Voice of the Wood: Halloween” genesis at 4 p.m. at the Stephens branch Library, 315 E. 14th St. in Davis.

    * Saturday, Oct. 13: The Avid Reader presents an upcoming event with Francis Pring-Mill and his recent engage “In Harmony with the Tao: A Guided Journey into the Tao Te Ching.” The hour-long event begins at 7:30 p.m. at The Avid Reader, 617 Second St. in downtown Davis. It is free and open to the public. call 530-758-4040 or visit avidreaderbooks.com for more information.

    * Saturday, Oct. 13 — Sunday, Oct. 14: Just as CPR helps you assist an individual having a heart attack, Mental Health First Aid helps you assist someone experiencing a mental health or substance use-related crisis. Learn risk factors and warning signs for mental health and addiction concerns, strategies for how to allay someone in exigency and non-crisis situations, and where to turn for help. There is no cost, but it organizers request registration for this two-day class at davis.shambhala.org so they Have an strategy of attendance. Meet from 8:30 a.m. to 1 p.m. Saturday, and 12:30 to 5 p.m. Sunday at Davis Shambhala Meditation Center, 133 D St., Suite H (above First Northern Bank).

    * Tuesday, Oct. 16: Free your body, intelligence and heart: exercise your breath with gentle Viniyoga movement and meditations from the Sutra on replete Awareness of Breathing to lower stress and build kindful resilience at Davis Shambhala Meditation Center, 133 D St., from 6 to 7 p.m. on every Tuesday. Drop in or call 415-315-9871 for info.

    * Tuesday, Oct. 16: The Davis Genealogy Club invites the public to a free presentation by well-liked returning speaker, genealogist James Baker, on “The Best Online Sites for German Genealogy” at 1 p.m. at the Davis Senior Center, 646 A St. Visit DavisGenealogy.org for more or call Lisa Henderson at 530-753-8943.

    * Wednesday, Oct. 17: The Korean Language and Culture Class, meets at 4 p.m. in the Stephens branch Library, 315 E. 14th St. in Davis. This group is for adults who wish to gain a basic erudition of Korean language and culture.

    * Saturday, Oct. 20: The Davis Phoenix Coalition will host a free Upstander Carnival for pre-K through elementary-aged children from 10 a.m. to 1 p.m. Saturday, Oct. 20, at the Davis Central Park 401 C St. familiar carnival games will feature an added ingredient of learning to breathe an “upstander” — someone who stands up to bullying.  There moreover will breathe free prizes, tote-bag giveaways to early arrivers and a bounce house. Sponsors are sought who share in the mission of promoting safe and inclusive spaces for bar None to allay as volunteers and to share information about their organization. For more information, email [email protected]

    * Saturday, Oct. 20: A fermented foods workshop, “Building Community Ferment,” begins at 11 a.m. at the Stephens branch Library, 315 E. 14th St. in Davis.

    * Saturday, Oct. 20:  Davis Origami Group meets at 1 p.m.at the Stephens branch Library, 315 E. 14th St. in Davis. bar None can learn to fold paper into different shapes. The first hour is for beginners and it is open to bar None ages and abilities.

    * Saturday, Oct. 20: Caturday at the Library begins at 2 p.m. at the Stephens branch Library, 315 E. 14th St. in Davis. This is an afternoon of joyful celebration of the pets in their lives, including kitten and cat adoptions, a showing of the documentary “Kedi,” a cat-themed family myth time, kitty cat crafts for kids and adults (including origami with the Davis Origami Group), and cat and dog mini-lectures by UC Davis School of Veterinary Medicine’s Melissa Bain, Emma Grigg, and Mikel Delgado.

    * Sunday, Oct. 21: Yolo County Master Gardeners meet at 2 p.m. at the Stephens branch Library, 315 E. 14th St. in Davis. bar None are invited to bring gardening questions and learn better gardening techniques.

    * Tuesday, Oct. 23: Free your body, intelligence and heart: exercise your breath with gentle Viniyoga movement and meditations from the Sutra on replete Awareness of Breathing to lower stress and build kindful resilience at Davis Shambhala Meditation Center, 133 D St., from 6 to 7 p.m. on every Tuesday. Drop in or call 415-315-9871 for info.

    * Wednesday, Oct. 24: The Hanna and Herbert Bauer Memorial Garden will host a free worm composting class from 5:15 to 6:30 p.m. at 137 N. Cottonwood St. in Woodland, featuring UC Master Gardene Steve Radosevich, who will breathe bringing worms to give away to participants. The city of Woodland will moreover breathe in attendance to deal free countertop compost buckets for the kitchen. Classes are offered for free throughout the year at the Community Garden.  To learn more about the garden activities and classes, visit www.yolocounty.org/garden. Pre-registration by Oct. 23 is required. To register, contact David Linebarger at 530-666-8429 or [email protected].  Participants are encouraged to dress appropriately for the weather and wear shoes that can find dirty. In the event of steady rain, the class will breathe cancelled.

    * Wednesday, Oct. 24: The Korean Language and Culture Class, meets at 4 p.m. in the Stephens branch Library, 315 E. 14th St. in Davis. This group is for adults who wish to gain a basic erudition of Korean language and culture.

    * Tuesday, Oct. 30: Free your body, intelligence and heart: exercise your breath with gentle Viniyoga movement and meditations from the Sutra on replete Awareness of Breathing to lower stress and build kindful resilience at Davis Shambhala Meditation Center, 133 D St., from 6 to 7 p.m. on every Tuesday. Drop in or call 415-315-9871 for info.

    * Wednesday, Oct. 31: The Korean Language and Culture Class, meets at 4 p.m. in the Stephens branch Library, 315 E. 14th St. in Davis. This group is for adults who wish to gain a basic erudition of Korean language and culture.

    * Sunday, Nov. 4: The Davis Chocolate Festival, organized and hosted by the Davis Odd Fellows Lodge, is back for its third successive year. The event will dash from 3 to 6 p.m. on both floors of the Odd Fellows Lodge, 415 Second St. in downtown Davis. Tickets are $7, available at Avid Reader Active, 605 Second St., at Common Grounds, 2171 Cowell Blvd., and at https://OddFellowsChocolateFest.Eventbrite.com.

    * Thursday, Nov. 6: Sutter keeping at Home Hospice offers a Grief and the Holidays workshops in Davis from 6:30 to 8 p.m. Adults who Have lost a loved one and are anticipating having a difficult time at the holidays are invited to this workshop. The workshops are available to bar None community members regardless of whether their loved one received hospice care. There is no imbue to join. For information and to pre-enroll, call Bereavement Services at 916-388-6215 or 916-388-6243.

    * Wednesday, Nov. 14: Travis Credit Union’s free fiscal literacy series features “Budgeting for Homeownership” at 6 p.m. in the Blanchard room at the Stephens branch Library, 315 E. 14th St. in Davis. This seminar presents valuable tips about poignant and settling into a recent house, keeping records, communicating with your lender and creditors, making sure your recent home is energy-efficient to redeem money, taking advantage of the fiscal benefits of owning a home, hiring a contractor if you pick to remodel, improving your credit score if you pick to refinance and more.

    Related


    Forensic Science Isn’t Science | killexams.com existent questions and Pass4sure dumps

    Still photo from CSI. The CSI effect has led American jurors today to await a constant parade of forensic evidence during trials and to spurn to believe that this evidence might ever breathe faulty.

    Photo by Monty Brinton/CBS Broadcasting

    Nine days before death row inmate Earl Washington’s scheduled execution, his lawyers informed the state of Virginia that it was about to murder an innocent man. Forensic analysis of semen introduced at trial had convinced the jury that Washington, whose mental abilities matched those of a 10-year-old, had brutally raped and murdered a young woman in 1982. Washington’s lawyers uncovered evidence that the analysis was faulty. The state halted the impending execution, and following a gubernatorial pardon, Washington was released from prison in 2001. He had been there for 17 years.

    Mark Joseph SternMark Joseph Stern

    Mark Joseph Stern covers courts and the law for Slate.

    How could forensic evidence, widely seen as factual and unbiased, nearly send an innocent person to his death? The concede is profoundly disturbing—and suggests that for every Earl Washington freed, untold more are sent to their deaths. Far from an infallible science, forensics is a decades-long experiment in which undertrained lab workers jettison the scientific routine in favor of speedy results that proper prosecutors’ hunches. No one knows exactly how many people Have been wrongly imprisoned—or executed—due to flawed forensics. But the number, most experts agree, is horrifyingly high. The most respected scientific organization in the country has revealed how deeply, fundamentally unscientific forensics is. A complete overhaul of their evidence analysis is desperately needed. Without it, the number of falsely convicted will only withhold growing.

    Behind the myriad technical defects of modern forensics equivocate two extremely basic scientific problems. The first is a pretty pellucid case of cognitive bias: A startling number of forensics analysts are told by prosecutors what they reflect the result of any given test will be. This isn’t mere prosecutorial mischief; analysts often await for as much information about the case as possible—including the identity of the suspect—claiming it helps them know what to learn for. Even the most upright analyst is liable to breathe subconsciously swayed when she already has a conclusion in mind. Yet few forensics labs supervene the typical blind experiment model to purge bias. Instead, they reenact a small-scale version of Inception, in which analysts are unconsciously convinced of their conclusion before their experiment even begins.

    The second flaw that plagues forensics is even more alarming: For decades, nobody knew how accurate forensic analyses were, or whether they were accurate at all. There’s no central agency that evaluates each test for precision or reliability before approving its use, and most were developed with barely a gesticulation toward the scientific routine and with cramped input from the scientific community. Nor did the creators of forensics tests publish their methods in peer-reviewed scientific journals. And why should they? Without a government agency overseeing the field, forensic analysts had no incentive to subject their tests to stricter scrutiny. Groups such as the Innocence Project Have continually do pressure on the Department of Justice—which almost certainly should Have supervised crime labs from the start—to regulate forensics. But until recently, no agency has been willing to wade into the decentralized mess that hundreds of labs across the country had unintentionally created.

    It might sound astonishing that undependable forensic tests Have been able to slip through the cracks for so many decades. But in light of their origin and use, it’s really no surprise at all. Unlike medical diagnostic tools—which undergo rigorous testing by government agencies—forensic analyses are developed exclusively for law enforcement. Almost everybody will requisite a cancer screening some day, but you won’t requisite a semen analysis until you’re convicted of rape. So long as forensics remains the sole province of law enforcement, police and prosecutors Have no incentive to screen their tests for accuracy once they’ve been adopted. Exposing a defective test might breathe vital exposing a wrongful prosecution, and few prosecutors are keen to admit that they might breathe sending innocent people to prison.

    The report amounted to a searing condemnation of forensics and a warning that death row may breathe filled with innocents.

    In 2009, a National Academy of Sciences committee embarked on a long-overdue quest to study typical forensics analyses with an confiscate level of scientific scrutiny—and the results were deeply chilling. Aside from DNA analysis, not a single forensic drill held up to rigorous inspection. The committee condemned common methods of fingerprint and hair analysis, questioning their accuracy, consistent application, and general validity. Bite-mark analysis—frequently employed in rape and murder cases, including capital cases—was subject to special scorn; the committee questioned whether gnaw marks could ever breathe used to positively identify a perpetrator. Ballistics and handwriting analysis, the committee noted, are moreover based on tenuous and largely untested science. The report amounted to a searing condemnation of the current drill of forensics and an ominous warning that death row may breathe filled with innocents.

    Given the flimsy foundation upon which the province of forensics is based, you might wonder why judges still allow it into the courtroom. The rather depressing concede is a combination of ignorance and laziness. In 1993, the Supreme Court announced a recent test, dubbed the “Daubert standard,” to allay federal judges determine what scientific evidence is trustworthy enough to breathe introduced at trial. The Daubert standard was meant to separate the judicial process from the quest for scientific truths—but it wound up frustrating judges and scientists alike. As one dissenter griped, the recent test essentially turned judges into “amateur scientists,” forced to sift through competing theories to determine what is truly scientific and what is not.

    The Daubert court clearly had cramped understanding of the complex, often contentious trial and oversight that goes into the establishment of an accepted scientific technique. It instructed judges to learn to “the existence and maintenance of standards controlling [the technique’s] operation,” a strikingly opaque command tossed off with cramped explanation. Even more puzzlingly, the recent standards called for judges to await “whether [the technique] has attracted widespread acceptance within a apropos scientific community”—which, as a frustrated federal arbiter pointed out, required judges to play referee between “vigorous and sincere disagreements” about “the very cutting edge of scientific research, where fact meets theory and assurance dissolves into probability.”

    Faced with this unenviable chore, most judges Have simply trusted prosecutors not to interpolate anything that wouldn’t roughly proper the Daubert standard. The conventional wisdom is that, if a prosecutor introduces any truly egregious pseudoscience, the defense can interpolate its own expert to refute it or can undermine it through aggressive questioning. It’s a comforting idea: Presented with conflicting scientific findings, jurors will sift out the truth.

    Unfortunately, it is moreover entirely false. American jurors today await a constant parade of forensic evidence during trials. They moreover spurn to believe that this evidence might ever breathe faulty. Lawyers call this the CSI effect, after the well-liked procedural that portrays forensics as the ultimate truth in crime investigation.

    “Once a jury hears something scientific, there’s a benign of mythical infallibility to it,” Peter Neufeld, a co-founder of the Innocence Project, told me. “That’s the association when a person in white lab coat takes the witness stand. By that point—once the jury’s heard it—it’s too late to convince them that maybe the science isn’t so infallible.”

    If judges can’t breathe trusted to withhold spurious forensic analysis out of the courtroom, and juries can’t breathe trusted to disregard it, then how are they going to withhold the next Earl Washington off death row? One option would breathe to permit anybody convicted on the basis of biological evidence to subject that evidence to DNA analysis—which is, after all, the one figure of forensics that scientists harmonize actually works. But in 2009, the Supreme Court ruled that convicts had no such constitutional right, even where they can Show a reasonable probability that DNA analysis would prove their innocence. (The ruling was 5–4, with the usual suspects lining up against convicts’ rights.)

    That leaves one eventual option: reforming the sprawling province of forensics itself. For years, this job proved nearly impossible, due in great piece to what the National Academy of Sciences called the “extreme disaggregation” of forensics. Until lab technicians supervene some uniform guidelines and abandon the dubious techniques glamorized on shows dote CSI, forensic science will barely qualify as a science at all. As a recent investigation by Chemical & Engineering tidings revealed, cramped progress has been made in the five years since the National Academy of Sciences condemned modern forensic techniques.

    There is, however, some hope on the horizon. The Obama administration has started to aggregate forensics practices, creating a National Commission on Forensic Science to develop uniform standards to breathe used across the country. The National Institute of Justice has moreover given out more than $100 million to fund research into the efficacy and consistency of commonly used forensics techniques.* More and more, labs across the country will know which methods of forensic analysis are trustworthy—and which are glorified pseudoscience.

    But what about those thousands of people who’ve already been do behind bars based on evidence analysis that they know today to breathe utterly unreliable? Even those inmates fortunate enough to obtain capable counsel will often requisite access to biological evidence, which the Supreme Court has refused to grant them. Every state provides post-conviction DNA access in theory, but many states restrict access after a few years—which is sure to leave some innocent prisoners marooned on death row. Their national experiment in untested forensics may soon breathe coming to a close. But it hasn’t ended in time to avert a few more people dote Earl Washington from being sacrificed on the altar of pseudoscience.

    *Correction, June 11, 2014: This article originally understated the amount of funding the National Institute of Justice has distributed for research on forensic techniques. (Return.)



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